Bisnucleophiles
WebFeb 4, 2010 · A novel PPh 3 -catalyzed (4 + n) annulation of 2- (acetoxymethyl)buta-2,3-dienoates 1c − e with 1, n -bisnucleophiles ( n = 1, 2) has been developed to provide a … WebOct 26, 2024 · Herein, we report the efficient and facile use of 3-carboxamide oxindoles as 1,3-C,N bisnucleophiles in the reactions with α,β-unsaturated trifluoromethyl ketones, …
Bisnucleophiles
Did you know?
WebCobalt-Catalyzed Oxidative Isocyanide Insertion to Amine-Based Bisnucleophiles: Diverse Synthesis of Substituted 2-Aminobenzimidazoles, 2-Aminobenzothiazoles, and 2 … WebBrucellosis caused by Brucella suis rarely occurs in domestic animals other than pigs. Epidemics of brucellosis in people have been reported among packing-house workers, …
To a freshly prepared solution of sodium methoxide containing sodium (0.05 g, 2.4 mmol) dissolved in methanol (6 mL), cysteamine hydrochloride (0.13 g, mmol) was added. After stirring under N2 atmosphere for 30 min at r.t, imidate (1 mmol) was added. The mixture was stirred again until the total disappearance … See more To a stirred solution of imidate (13.5 g, 0.1 mol) and pyridine (8.84 mL, 0.11 mol) dissolved in dry Et2O (100 mL). Ethyl chloroformate … See more To a well-stirred solution of imidate (1 mmol) and a catalytic amount of acetic acid (1.7 μL) in Toluene (2 mL). Ethylenediamine (0.07 g, 1.2 mmoL) was added slowly. The reaction mixture was refluxed for 2 h. After … See more Viscous oil, yield: 89%. 1H-NMR (300 MHz, CDCl3) δ: 1.14 (s, 3H), 1.15 (s, 3H), 2.38 (sept, JH–H = 6 Hz, 1H), 3.39 (q, JH–H = 6 Hz, 2H); 3.70 (t, JH–H = 9 Hz, 2H). 13C NMR … See more Webchloride (12), readily reacted with bisnucleophiles such as primary amines or activated methylene compounds to form a five-membered heterocyclic ring annulated onto the benzene moiety in a one-pot reaction, we decided to apply this approach to synthesize isoindolin-1-ones 3 (phthalimidines) as well.
WebMar 1, 2008 · Reaction of 6-acetyl-7-(2-dimethylaminovinyl)pyrazolo[1,5-a]pyrimidine 1 with 1,3- and 1,4-bisnucleophiles has been investigated; obtainment of new polycyclic heterocyclic derivatives is reported.
WebTel: 0512-65883375; 15962208862. 课题组网站. 1998.9-2002.6 苏州大学化学化工学院学士. 2002.9-2007.6 苏州大学化学化工学院博士. 2005.12-2006.12 新加坡南洋理工大学助理研究员. （Research Associate, 新加坡科学院院士、马来西亚科学院院士Prof. Teck-Peng Loh）. 2007.8-2011.2 新加坡南洋 ...
WebAug 5, 2024 · The introduction of a methyl group and its 13 C and 2 H labeled analogs on Csp 2-centers remains a challenging issue in synthetic chemistry.While the photoredox/Ni dual catalysis has proven to constitute a valuable methodology for the forging of Csp 2 −Csp 3 bonds, the high difficulty to generate the methyl radical and to control its reactivity has … chinadns_ng smartdnsWebDec 1, 2005 · Reactions of acylimines of methyl trifluoropyruvate with C,N-bisnucleophiles gave fluoro-containing heterocycles including the 5-oxo-4,5-dihydro-1H-pyrrole fragment. Discover the world's research ... china dj lighting packagesWebOct 1, 2015 · Phosphine-catalyzed (3 + 2) and (3 + 3) annulations between 5-acetoxypenta-2,3-dienoate and 1C,3O-bisnucleophiles are presented. The former cases can be achieved with the assistance of base while ... chinadns 插件WebAbstract. A double allylic defluorinative alkylation reaction of 1,1-bisnucleophiles with (trifluoromethyl)alkenes is reported that occurs via the exclusively regioselective S N 2 … china dog bowls ukWebNov 6, 2024 · Brucellosis is an infectious disease caused by the bacterium Brucella abortus and is commonly transmitted between elk, bison, and domestic livestock. Many … grafton ps improvementWebOver the past few decades, transition metals have found wide applications in the development of selective oxidative transformations mediated by molecular oxygen. Due to the benign nature of molecular oxygen as an oxidant and an increasing awareness of green chemistry practice, tremendous progress has been made towards the development of Cu … china diy vinyl plank flooringWebA titanacarborane monoamide catalyzed, one-step synthesis of mono/bicyclic guanidines from commercially available di/triamines and carbodiimides is reported. The reaction mechanism is also proposed. grafton psychology associates limited